Effect of co-trimoxazole prophylaxis on morbidity and mortality of HIV-exposed, HIV-uninfected infants in South Africa: a randomised controlled, non-inferiority trial

• Main Authors: Brodie Daniels, PhD (Author), Anna Coutsoudis, ProfPhD (Author), Eshia Moodley-Govender, PhD (Author), Helen Mulol, PhD (Author), Elizabeth Spooner, MBBCh (Author), Photini Kiepiela, PhD (Author), Shabashini Reddy, MSc (Author), Linda Zako, MBChB (Author), Nhan T Ho, PhD (Author), Louise Kuhn, ProfPhD (Author), Gita Ramjee, PhD (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: WHO guidelines recommend co-trimoxazole prophylaxis for HIV-exposed, HIV-uninfected infants. These guidelines date back to an era in which HIV testing of infants was impossible and mothers had poor access to antiretroviral treatment. To determine whether this guideline requires...