Ultrasound-Responsive Materials for Drug/Gene Delivery

Ultrasound is one of the most commonly used methods in the diagnosis and therapy of diseases due to its safety, deep penetration into tissue, and non-invasive nature. In the drug/gene delivery systems, ultrasound shows many advantages in terms of site-specific delivery and spatial release control of...

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Bibliographic Details
Main Authors: Xiaowen Cai (Author), Yuan Jiang (Author), Mei Lin (Author), Jiyong Zhang (Author), Huanhuan Guo (Author), Fanwen Yang (Author), Wingnang Leung (Author), Chuanshan Xu (Author)
Format: Book
Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
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Summary:Ultrasound is one of the most commonly used methods in the diagnosis and therapy of diseases due to its safety, deep penetration into tissue, and non-invasive nature. In the drug/gene delivery systems, ultrasound shows many advantages in terms of site-specific delivery and spatial release control of drugs/genes and attracts increasing attention. Microbubbles are the most well-known ultrasound-responsive delivery materials. Recently, nanobubbles, droplets, micelles, and nanoliposomes have been developed as novel carriers in this field. Herein, we review advances of novel ultrasound-responsive materials (nanobubbles, droplets, micelles and nanoliposomes) and discuss the challenges of ultrasound-responsive materials in delivery systems to boost the development of ultrasound-responsive materials as delivery carriers.
Item Description:1663-9812
10.3389/fphar.2019.01650