Radiosynthesis of Stable ¹⁹⁸Au-Nanoparticles by Neutron Activation of α_vβ₃-Specific AuNPs for Therapy of Tumor Angiogenesis

• Principais autores: Güllü Davarci (Autor), Carmen Wängler (Autor), Klaus Eberhardt (Autor), Christopher Geppert (Autor), Ralf Schirrmacher (Autor), Robert Freudenberg (Autor), Marc Pretze (Autor), Björn Wängler (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as a therapeutic option for the treatment of cancer with high tumor angiogenesis. The AuNPs were designed with different mono- or dithiol-ligands and decorated with different am...