Radiosynthesis of Stable ¹⁹⁸Au-Nanoparticles by Neutron Activation of α_vβ₃-Specific AuNPs for Therapy of Tumor Angiogenesis

• Main Authors: Güllü Davarci (Author), Carmen Wängler (Author), Klaus Eberhardt (Author), Christopher Geppert (Author), Ralf Schirrmacher (Author), Robert Freudenberg (Author), Marc Pretze (Author), Björn Wängler (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as a therapeutic option for the treatment of cancer with high tumor angiogenesis. The AuNPs were designed with different mono- or dithiol-ligands and decorated with different am...