CD44/Folate Dual Targeting Receptor Reductive Response PLGA-Based Micelles for Cancer Therapy

• Автори: Ru Zhang (Автор), Yunying Jiang (Автор), Linkun Hao (Автор), Yang Yang (Автор), Ying Gao (Автор), Ningning Zhang (Автор), Xuecheng Zhang (Автор), Yimin Song (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

In this study, a novel poly (lactic-co-glycolic acid) (PLGA)-based micelle was synthesized, which could improve the therapeutic effect of the antitumor drug doxorubicin hydrochloride (DOX) and reduce its toxic and side effects. The efficient delivery of DOX was achieved by active targeting mediated...