Baicalein inhibits the pharmacokinetics of simvastatin in rats via regulating the activity of CYP3A4
Context Baicalein and simvastatin possess similar pharmacological activities and indications. The risk of their co-administration was unclear. Objective The interaction between baicalein and simvastatin was investigated to provide reference and guidance for the clinical application of the combinatio...
Saved in:
Main Authors: | Meng Meng (Author), Xin Li (Author), Xiuwen Zhang (Author), Bin Sun (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2021-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Regulation of bone formation by baicalein via the mTORC1 pathway
by: Li SF, et al.
Published: (2015) -
Pharmacokinetic interaction between rhynchopylline and pellodendrine via CYP450 enzymes and P-gp
by: Qingzhen Meng, et al.
Published: (2021) -
Baicalein Ameliorates Aβ-Induced Memory Deficits and Neuronal Atrophy via Inhibition of PDE2 and PDE4
by: Jing Shi, et al.
Published: (2021) -
The Chinese herb Styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal CYP3A
by: Feng Zhang, et al.
Published: (2022) -
Effect of Pomelo Juice on the Pharmacokinetics of Simvastatin, CYP3A2 Activity and Mdr1a, Mdr1b and Slc21a5 Expressions in Rats
by: Kritsakorn Rayasilp, et al.
Published: (2019)