Ang II Promotes Cardiac Autophagy and Hypertrophy via Orai1/STIM1

• Main Authors: Chang-Bo Zheng (Author), Wen-Cong Gao (Author), Mingxu Xie (Author), Zhichao Li (Author), Xin Ma (Author), Wencong Song (Author), Dan Luo (Author), Yongxiang Huang (Author), Jichen Yang (Author), Peng Zhang (Author), Yu Huang (Author), Weimin Yang (Author), Xiaoqiang Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathophysiology of cardiac hypertrophy is complex and multifactorial. Both the store-operated Ca2+ entry (SOCE) and excessive autophagy are the major causative factors for pathological cardiac hypertrophy. However, it is unclear whether these two causative factors are interdependent. In this stu...