Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• المؤلفون الرئيسيون: K. Esparza (مؤلف), S. D. Oliveira (مؤلف), M. Castellon (مؤلف), R. D. Minshall (مؤلف), H. Onyuksel (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2023-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...