Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• Κύριοι συγγραφείς: K. Esparza (Συγγραφέας), S. D. Oliveira (Συγγραφέας), M. Castellon (Συγγραφέας), R. D. Minshall (Συγγραφέας), H. Onyuksel (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Hindawi Limited, 2023-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...