Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• मुख्य लेखकों: K. Esparza (लेखक), S. D. Oliveira (लेखक), M. Castellon (लेखक), R. D. Minshall (लेखक), H. Onyuksel (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...