Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• Váldodahkkit: K. Esparza (Dahkki), S. D. Oliveira (Dahkki), M. Castellon (Dahkki), R. D. Minshall (Dahkki), H. Onyuksel (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2023-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...