Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

• Asıl Yazarlar: K. Esparza (Yazar), S. D. Oliveira (Yazar), M. Castellon (Yazar), R. D. Minshall (Yazar), H. Onyuksel (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2023-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...