Cover Image

Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress

Liwei Hang, 1–5,* Yan Peng, 6,* Rui Xiang, 7 Xiangdong Li, 8 Zhiliang Li 1–4 1Department of Cardiology, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, People’s Republic of China; 2Laboratory of Heart Center and Department of C...

Full description

Saved in:

Bibliographic Details
Main Authors:	Hang L (Author), Peng Y (Author), Xiang R (Author), Li X (Author), Li Z (Author)
Format:	Book
Published:	Dove Medical Press, 2020-02-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Astragaloside IV protects endothelial progenitor cells from the damage of ox-LDL via the LOX-1/NLRP3 inflammasome pathway
by: Qian W, et al.
Published: (2019)

Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
by: Tianyuan Ye, et al.
Published: (2018)

CRP-Induced NLRP3 Inflammasome Activation Increases LDL Transcytosis Across Endothelial Cells
by: Fang Bian, et al.
Published: (2019)

Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome
by: Ning-ning Wang, et al.
Published: (2022)

ox-LDL-Induced Endothelial Progenitor Cell Oxidative Stress via p38/Keap1/Nrf2 Pathway
by: Qijun Jiang, et al.
Published: (2022)

Induction of Apoptosis by Hypertension Via Endoplasmic Reticulum Stress
by: Yingying Sun, et al.
Published: (2015)

LOX-1, OxLDL, and Atherosclerosis
by: Angela Pirillo, et al.
Published: (2013)

miR-155 Promotes ox-LDL-Induced Autophagy in Human Umbilical Vein Endothelial Cells
by: Zhaozhi Zhang, et al.
Published: (2017)

Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs
by: Shan Liu, et al.
Published: (2021)

ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes
by: Pei-pei Fang, et al.
Published: (2020)

Endoplasmic Reticulum
Published: (2019)

Oridonin alleviates the inhibitory effect of lipopolysaccharide on the proliferation and osteogenic potential of periodontal ligament stem cells by inhibiting endoplasmic reticulum stress and NF-κB/NLRP3 inflammasome signaling
by: Junhao Jiang, et al.
Published: (2023)

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway
by: Zhongsheng Zhu, et al.
Published: (2019)

13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells
by: Zhihua Peng, et al.
Published: (2020)

Evidence-based antioxidant activity of the essential oil from Fructus A. zerumbet on cultured human umbilical vein endothelial cells' injury induced by ox-LDL
by: Shen Xiang-chun, et al.
Published: (2012)

Assessment of oxLDL, anti-oxLDL antibodies and lipoprotein-associated phospholipase A2 as cardiovascular risk markers in obese adolescents with and without T1DM
by: Nesreen N. Omar, et al.
Published: (2017)

ROS and Endoplasmic Reticulum Stress in Pulmonary Disease
by: Xiangning Cui, et al.
Published: (2022)

Monosialoganglioside protects against bupivacaine-induced neurotoxicity caused by endoplasmic reticulum stress in rats
by: Liu B, et al.
Published: (2019)

Endoplasmic Reticulum Dysfunction: An Emerging Mechanism of Vitiligo Pathogenesis
by: Xie Y, et al.
Published: (2024)

Protective effects of mitochondrial fission inhibition on ox-LDL induced VSMC foaming via metabolic reprogramming
by: Yijin Fang, et al.
Published: (2022)

Mesoporous tantalum oxide nanomaterials induced cardiovascular endothelial cell apoptosis via mitochondrial-endoplasmic reticulum stress apoptotic pathway
by: Yuanyong Jiao, et al.
Published: (2023)

Sinapine Thiocyanate Ameliorates Vascular Endothelial Dysfunction in Hypertension by Inhibiting Activation of the NLRP3 Inflammasome
by: Yang Liu, et al.
Published: (2021)

Methyl-β-cyclodextrin suppresses the monocyte-endothelial adhesion triggered by lipopolysaccharide (LPS) or oxidized low-density lipoprotein (oxLDL)
by: Guo Chen, et al.
Published: (2021)

High T3 Induces β-Cell Insulin Resistance via Endoplasmic Reticulum Stress
by: Bo Liang, et al.
Published: (2020)

Role of NADPH Oxidase 4 in Corneal Endothelial Cells Is Mediated by Endoplasmic Reticulum Stress and Autophagy
by: Dae Joong Ma, et al.
Published: (2023)

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis
by: Anastasia V. Poznyak, et al.
Published: (2021)

lnc-MRGPRF-6:1 Promotes ox-LDL-Induced Macrophage Ferroptosis via Suppressing GPX4
by: Zhihuan You, et al.
Published: (2023)

Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE−/− Mice by Regulating PPARγ/FAK Signaling Pathway
by: Jianan Geng, et al.
Published: (2020)

Ox-LDL Promotes Migration and Adhesion of Bone Marrow-Derived Mesenchymal Stem Cells via Regulation of MCP-1 Expression
by: Fenxi Zhang, et al.
Published: (2013)

Salvianolic Acid B and Ginsenoside Re Synergistically Protect Against Ox-LDL-Induced Endothelial Apoptosis Through the Antioxidative and Antiinflammatory Mechanisms
by: Ke Yang, et al.
Published: (2018)

Mechanisms of CFTR folding at the endoplasmic reticulum
by: Soo Jung Kim, et al.
Published: (2012)

RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress
by: Xiao Chen, et al.
Published: (2022)

Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis
by: Zhixiao Yao, et al.
Published: (2019)

SNHG1 Inhibits ox-LDL-Induced Inflammatory Response and Apoptosis of HUVECs via Up-Regulating GNAI2 and PCBP1
by: Yuan Lu, et al.
Published: (2020)

Increased Serum ox-LDL Levels Correlated with Lung Function, Inflammation, and Oxidative Stress in COPD
by: Yongchun Shen, et al.
Published: (2013)

Photothermal Therapy via NIR II Light Irradiation Enhances DNA Damage and Endoplasmic Reticulum Stress for Efficient Chemotherapy
by: Qingduo Kong, et al.
Published: (2021)

Homocysteine promotes atherosclerosis through macrophage pyroptosis via endoplasmic reticulum stress and calcium disorder
by: Shan Zhang, et al.
Published: (2023)

Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome
by: Chen Mei, et al.
Published: (2021)

The protective effects of angelica organic acid against ox-LDL-induced autophagy dysfunction of HUVECs
by: Xuefeng Li, et al.
Published: (2020)

The Impairment of Endothelial Autophagy Accelerates Renal Senescence by Ferroptosis and NLRP3 Inflammasome Signaling Pathways with the Disruption of Endothelial Barrier
by: Jin Won Kim, et al.
Published: (2024)