Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis

• Main Authors: Toshinori Hirai (Author), Yukari Mori (Author), Toru Ogura (Author), Yuki Kondo (Author), Yuka Sakazaki (Author), Yoichi Ishitsuka (Author), Akihiro Sudo (Author), Takuya Iwamoto (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that promote urinary calcium excretion. Methods Japanese Spontaneous Adverse Drug Event Reports was analyzed to examine signals for denosumab-induced hypocalcaemia co-administ...