Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex

• Main Authors: Paola Devoto (Author), Claudia Sagheddu (Author), Michele Santoni (Author), Giovanna Flore (Author), Pierluigi Saba (Author), Marco Pistis (Author), Gian Luigi Gessa (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous results indicate that dopamine (DA) release in the medial prefrontal cortex (mPFC) is modified by α2 adrenoceptor- but not D2 DA receptor- agonists and antagonists, suggesting that DA measured by microdialysis in the mPFC originates from noradrenergic terminals. Accordingly, noradrenergic d...