Application of In Silico Filtering and Isothermal Titration Calorimetry for the Discovery of Small Molecule Inhibitors of MDM2
The initial discovery phase of protein modulators, which consists of filtering molecular libraries and in vitro direct binding validation, is central in drug discovery. Thus, virtual screening of large molecular libraries, together with the evaluation of binding affinity by isothermal calorimetry, g...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2022-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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