LncRNA-GAS5 Inhibits Expression of miR 103 and Ameliorates the Articular Cartilage in Adjuvant-Induced Arthritis in Obese Mice

• Main Authors: Hongwei Chen (Author), Chuan He (Author), Yan Liu (Author), Xiaolin Li (Author), Chaoju Zhang (Author), Qunyan Qin (Author), Qixiong Pang (Author)
• Format: Book
• Published: SAGE Publishing, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We explored whether long noncoding RNA growth arrest-specific transcript 5 (LncRNA-GAS5) small interfering RNA (siRNA) reduced cartilage destruction in obese mice with adjuvant-induced arthritis. We studied the effects of LncRNA-GAS5 siRNA on the polyarthritis index; hind paw swelling; and the serum...