Antineoplastic Activity of Water-Soluble Form of Novel Kinase Inhibitor 1-(4-Chlorobenzyl)-3-chloro-4-(3-trifluoromethylphenylamino)-1<i>H</i>-pyrrole-2,5-dione immobilized on Polymeric Poly(PEGMA-<i>co</i>-DMM) Carrier
The maleimide derivative 1-(4-chlorobenzyl)-3-chloro-4-(3-trifluoromethylphenylamino)-1<i>H</i>-pyrrole-2,5-dione (MI-1) was synthesized as inhibitor of several protein kinases, however, its application is hindered by its poor water solubility. In this study, the mechanisms of the antine...
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Main Authors: | Nataliya Finiuk (Author), Olga Klyuchivska (Author), Nataliya Mitina (Author), Halyna Kuznietsova (Author), Kateryna Volianiuk (Author), Alexander Zaichenko (Author), Volodymyr Rybalchenko (Author), Rostyslav Stoika (Author) |
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Format: | Book |
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MDPI AG,
2022-01-01T00:00:00Z.
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