Applications of calixarenes in cancer chemotherapy: facts and perspectives

Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. T...

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Main Authors: Yousaf A (Author), Abd Hamid S (Author), Bunnori NM (Author), Ishola AA (Author)
Format: Book
Published: Dove Medical Press, 2015-06-01T00:00:00Z.
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100 1 0 |a Yousaf A  |e author 
700 1 0 |a Abd Hamid S  |e author 
700 1 0 |a Bunnori NM  |e author 
700 1 0 |a Ishola AA  |e author 
245 0 0 |a Applications of calixarenes in cancer chemotherapy: facts and perspectives 
260 |b Dove Medical Press,   |c 2015-06-01T00:00:00Z. 
500 |a 1177-8881 
520 |a Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief. Keywords: cancer, chemotherapy, calixarenes 
546 |a EN 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Drug Design, Development and Therapy, Vol 2015, Iss default, Pp 2831-2838 (2015) 
787 0 |n http://www.dovepress.com/applications-of-calixarenes-in-cancer-chemotherapy-facts-and-perspecti-peer-reviewed-article-DDDT 
787 0 |n https://doaj.org/toc/1177-8881 
856 4 1 |u https://doaj.org/article/10ea95bb470a4075af34b8403db7b58d  |z Connect to this object online.