Proteomic Profiling Identifies Distinct Regulation of Proteins in Obese Diabetic Patients Treated with Metformin

• Main Authors: Awad Alshahrani (Author), Ahmad Aljada (Author), Afshan Masood (Author), Muhammad Mujammami (Author), Assim A. Alfadda (Author), Mohthash Musambil (Author), Ibrahim O. Alanazi (Author), Mohammed Al Dubayee (Author), Anas M. Abdel Rahman (Author), Hicham Benabdelkamel (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background</b>: Obesity and type 2 diabetes mellitus (T2DM) are characterized by underlying low-grade chronic inflammation. Metformin has been used as the first line of therapy in T2DM as it decreases hepatic glucose production and glucose intestinal absorption, enhances insulin sensi...