Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• المؤلفون الرئيسيون: Ožbej Zupančič (مؤلف), Josip Matić (مؤلف), Aygün Doğan (مؤلف), Alessio Gaggero (مؤلف), Johannes Khinast (مؤلف), Amrit Paudel (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...