Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Hauptverfasser: Ožbej Zupančič (Verfasst von), Josip Matić (Verfasst von), Aygün Doğan (Verfasst von), Alessio Gaggero (Verfasst von), Johannes Khinast (Verfasst von), Amrit Paudel (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2024-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...