Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Príomhchruthaitheoirí: Ožbej Zupančič (Údar), Josip Matić (Údar), Aygün Doğan (Údar), Alessio Gaggero (Údar), Johannes Khinast (Údar), Amrit Paudel (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2024-09-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...