Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Autori principali: Ožbej Zupančič (Autore), Josip Matić (Autore), Aygün Doğan (Autore), Alessio Gaggero (Autore), Johannes Khinast (Autore), Amrit Paudel (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2024-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...