Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• 主要な著者: Ožbej Zupančič (著者), Josip Matić (著者), Aygün Doğan (著者), Alessio Gaggero (著者), Johannes Khinast (著者), Amrit Paudel (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...