Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Main Authors: Ožbej Zupančič (Author), Josip Matić (Author), Aygün Doğan (Author), Alessio Gaggero (Author), Johannes Khinast (Author), Amrit Paudel (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2024-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...