Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Главные авторы: Ožbej Zupančič (Автор), Josip Matić (Автор), Aygün Doğan (Автор), Alessio Gaggero (Автор), Johannes Khinast (Автор), Amrit Paudel (Автор)
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• Опубликовано: MDPI AG, 2024-09-01T00:00:00Z.
• Предметы: article
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<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...