Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Váldodahkkit: Ožbej Zupančič (Dahkki), Josip Matić (Dahkki), Aygün Doğan (Dahkki), Alessio Gaggero (Dahkki), Johannes Khinast (Dahkki), Amrit Paudel (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2024-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...