Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients

• Main Authors: César de la Fuente-Núñez (Author), Sarah C. Mansour (Author), Zhejun Wang (Author), Lucy Jiang (Author), Elena B.M. Breidenstein (Author), Melissa Elliott (Author), Fany Reffuveille (Author), David P. Speert (Author), Shauna L. Reckseidler-Zenteno (Author), Ya Shen (Author), Markus Haapasalo (Author), Robert E.W. Hancock (Author)
• Format: Book
• Published: MDPI AG, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) patients often acquire chronic respiratory tract infections due to Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc) species. In the CF lung, these bacteria grow as multicellular aggregates termed biofilms. Biofilms demonstrate increased (adaptive) resistance to conv...