Intracerebroventricularly Injected Streptozotocin Exerts Subtle Effects on the Cognitive Performance of Long-Evans Rats

• Main Authors: Attila Gáspár (Author), Barbara Hutka (Author), Aliz Judit Ernyey (Author), Brigitta Tekla Tajti (Author), Bence Tamás Varga (Author), Zoltán Sándor Zádori (Author), István Gyertyán (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intracerebroventricularly injected streptozotocin (STZ)-induced learning impairment has been an increasingly used rat model of Alzheimer disease. The evoked pathological changes involve many symptoms of the human disease (cognitive decline, increase in β-amyloid and phospho-tau level, amyloid plaque...