The Efficacy of Posttreatment with Synthetic C-Reactive Protein in Murine Bacterial Peritonitis via Activation of FcγRI-Expressing Kupffer Cells

• Main Authors: Manabu Kinoshita (Author), Seigo Ito (Author), Takuya Ishikiriyama (Author), Kumiko Sekiguchi (Author), Ryota Yamaguchi (Author), Ryoichi Tsuruhara (Author), Akihisa Matsuda (Author), Kazuki Koiwa (Author), Masahiro Nakashima (Author), Hiroyuki Nakashima (Author), Masao Miyashita (Author), Shuhji Seki (Author)
• Format: Book
• Published: Karger Publishers, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pretreatment with synthetic C-reactive protein (CRP), a functional CRP peptide, has the potential to augment macrophage phagocytosis by bacterial challenge. However, the posttreatment is clinically ideal. We investigated the efficacy of posttreatment with synthetic CRP on murine cecal ligation and p...