Effect of Endurance Training on miR-196a and miR-133a Expression in Subcutaneous White Adipose Tissue of Wistar Rats

Purpose: The aim of current study was to investigate the effect of endurance training on expression of miR-196a and miR-133a in subcutaneous white adipose tissue (WAT). Methods: 16 wistar rats were divided into two groups included: 1) Control (n=8) and 2) Endurance Training (n=8). The subjects of tr...

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Main Authors: Saeed Daneshyar (Author), Mohammad Reza Kordi (Author), Mehdi Kadivar (Author), Samane Afshari (Author)
Format: Book
Published: Shahid Beheshti University, 2019-02-01T00:00:00Z.
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Summary:Purpose: The aim of current study was to investigate the effect of endurance training on expression of miR-196a and miR-133a in subcutaneous white adipose tissue (WAT). Methods: 16 wistar rats were divided into two groups included: 1) Control (n=8) and 2) Endurance Training (n=8). The subjects of training group underwent continues endurance training on treadmill for eight weeks. To measure of gene expression were used the Real Time (RT) -PCR method. Results: Data showed that gene expression of UCP1 was significantly higher in trained group than control (P0.05). Conclusions: The results of this study showed that the endurance training did not change the expression of miR-196a and miR-133a in subcutaneous WAT, indicating that the endurance training-induced the increase of UCP1 expression did not relate to change of miR-196a and miR-133a expression.
Item Description:2676-3710
2645-4041
10.52547/joeppa.12.1.1