Case Report: Various Clinical Manifestations Caused by Varicella-Zoster Virus in a Family

A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother's herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clin...

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Bibliographic Details
Main Authors: Qinghong Meng (Author), Bingsong Wang (Author), Xianlai Zhang (Author), Zhen Li (Author), Wenjie Wang (Author), Kaihu Yao (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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Summary:A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother's herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clinical presentation; however, his 28-year-old father presented with a typical generalized vesicular rash. His vaccinated 4-year-old sister was clinically mild, which could be defined as a breakthrough varicella case. They infected the same virus strain but presented various clinical forms.
Item Description:2296-2360
10.3389/fped.2022.876250