Prevalence of MPL (W515K/L) Mutations in Patients with Negative-JAK2 (V617F) Myeloproliferative Neoplasm in North-East of Iran

• Main Authors: Seyyede Fatemeh Shams (Author), Hossein Ayatollahi (Author), Mohammad hadi Sadeghian (Author), Monavar Afzal Aghaee (Author), Sepideh Shakeri (Author), Ehsan Yazdandoust (Author), Maryam Sheikhi (Author), Nafiseh Amini (Author), Samane Bakhshi (Author), Afsane Bahrami (Author)
• Format: Book
• Published: Iranian Society of Pathology, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objective: Janus kinase 2 (JAK2) and Myeloproliferative Leukemia (MPL) mutations are confirmatory indicators for Myeloproliferative Neoplasm (MPN). The current study was performed to determine the frequency of MPL mutation in MPN patients without JAK2 mutation, in order to assign MPL...