Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model

• Main Authors: Yun Zhang (Author), Katherine M. Weh (Author), Bridget A. Tripp (Author), Jennifer L. Clarke (Author), Connor L. Howard (Author), Shruthi Sunilkumar (Author), Amy B. Howell (Author), Laura A. Kresty (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We recently reported that cranberry proanthocyanidins (C-PACs) inhibit esophageal adenocarcinoma (EAC) by 83% through reversing reflux-induced bacterial, inflammatory and immune-implicated proteins and genes as well as reducing esophageal bile acids, which drive EAC progression. This study investiga...