Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells

• Main Authors: Julie Ng (Author), Anna E. Marneth (Author), Alec Griffith (Author), Daniel Younger (Author), Sailaja Ghanta (Author), Alan Jiao (Author), Gareth Willis (Author), Junwen Han (Author), Jewel Imani (Author), Bailin Niu (Author), Joshua W. Keegan (Author), Brandon Hancock (Author), Fei Guo (Author), Yang Shi (Author), Mark A. Perrella (Author), James A. Lederer (Author)
• Format: Book
• Published: Karger Publishers, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel therapeutics are urgently needed to prevent opportunistic infections in immunocompromised individuals undergoing cancer treatments or other immune-suppressive therapies. Trained immunity is a promising strategy to reduce this burden of disease. We previously demonstrated that mesenchymal strom...