Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles
RNA molecules have emerged as promising therapeutics. Like all other drugs, the safety profile and immune response are important criteria for drug evaluation. However, the literature on RNA immunogenicity has been controversial. Here, we used the approach of RNA nanotechnology to demonstrate that th...
Saved in:
Main Authors: | Sijin Guo (Author), Hui Li (Author), Mengshi Ma (Author), Jian Fu (Author), Yizhou Dong (Author), Peixuan Guo (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2017-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Rolling Circle Transcription of Tandem siRNA to Generate Spherulitic RNA Nanoparticles for Cell Entry
by: Peixuan Guo
Published: (2012) -
Long-term stability and immunogenicity of lipid nanoparticle COVID-19 mRNA vaccine is affected by particle size
by: Ruimeng Shi, et al.
Published: (2024) -
Characterization of Immunogenicity of Malignant Cells with Stemness in Intrahepatic Cholangiocarcinoma by Single-Cell RNA Sequencing
by: Jing Bian, et al.
Published: (2022) -
Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles
by: Lisa Haddick, et al.
Published: (2020) -
Stoichiometry of multi-specific immune checkpoint RNA Abs for T cell activation and tumor inhibition using ultra-stable RNA nanoparticles
by: Dan Shu, et al.
Published: (2021)