IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

• Main Authors: Fernando Botelho (Author), Anisha Dubey (Author), Ehab A. Ayaub (Author), Rex Park (Author), Ashley Yip (Author), Allison Humbles (Author), Roland Kolbeck (Author), Carl D. Richards (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interleukin-1 family member IL-33 participates in both innate and adaptive T helper-2 immune cell responses in models of lung disease. The IL-6-type cytokine Oncostatin M (OSM) elevates lung inflammation, Th2-skewed cytokines, alternatively activated (M2) macrophages, and eosinophils in C57Bl/6...