Varicella prevention in Costa Rica: impact of a one-dose schedule universal vaccination

Introduction: To describe the impact following a 1-dose Varicella vaccination schedule introduced in Costa Rica in September 2007. Areas covered: This is a retrospective review using epidemiologic surveillance national databases of varicella cases and hospitalizations, period 2000-2015. We analyzed...

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Main Authors: María L. Avila-Aguero (Author), Rolando Ulloa-Gutierrez (Author), Kattia Camacho-Badilla (Author), Alejandra Soriano-Fallas (Author), Roberto Arroba-Tijerino (Author), Ana Morice-Trejos (Author)
Format: Book
Published: Taylor & Francis Group, 2017-03-01T00:00:00Z.
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Summary:Introduction: To describe the impact following a 1-dose Varicella vaccination schedule introduced in Costa Rica in September 2007. Areas covered: This is a retrospective review using epidemiologic surveillance national databases of varicella cases and hospitalizations, period 2000-2015. We analyzed age-related varicella incidence cases and hospitalization trends before and after the vaccine introduction. Expert commentary: Varicella vaccine coverage among children 16 months age increased from 76% in 2008 to 95% in 2015. During this period Costa Rica reached a 73.8% reduction of Varicella reported cases and 85.9% reduction of hospitalizations in the general population. Among children under 5 years of age, that reduction was 79.1% and 87%, respectively. Varicella complications in hospitalized patients decreased 98%, from n = 53 in 2008 to n = 1 in 2014. After 8-years post implementation of a 1-dose schedule of universal varicella vaccination, a dramatic overall disease reduction in incidence, hospitalizations and complicated cases has been observed in all age groups.
Item Description:1476-0584
1744-8395
10.1080/14760584.2017.1247700