Pharmacokinetics of Human Red Blood Cell Microparticles Prepared Using High-Pressure Extrusion Method

• Main Authors: Wenche Jy (Author), Ashish K. Rehni (Author), Carlos Bidot (Author), Hever Navarro-Quero (Author), Conner R. Haase (Author), Sebastian Koch (Author), Yeon S. Ahn (Author), Kunjan R. Dave (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin in vitro and effective in arresting bleeding in animal bleeding models. However, prior to ascertaining the clinical efficacy of RMPs, detailed preclinical...