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p53-Mediated Oxidative Stress Enhances Indirubin-3'-Monoxime-Induced Apoptosis in HCT116 Colon Cancer Cells by Upregulating Death Receptor 5 and TNF-Related Apoptosis-Inducing Ligand Expression

Indirubin-3′-monoxime (I3M) exhibits anti-proliferative activity in various cancer cells; however, its anti-cancer mechanism remains incompletely elucidated. This study revealed that I3M promotes the expression of death receptor 5 (DR5) and tumor necrosis factor (TNF)-related apoptosis-ind...

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Main Authors:	Matharage Gayani Dilshara (Author), Ilandarage Menu Neelaka Molagoda (Author), Rajapaksha Gedara Prasad Tharanga Jayasooriya (Author), Yung Hyun Choi (Author), Cheol Park (Author), Kyoung Tae Lee (Author), Seungheon Lee (Author), Gi-Young Kim (Author)
Format:	Book
Published:	MDPI AG, 2019-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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