Aptamer-Mediated Codelivery of Doxorubicin and NF-κB Decoy Enhances Chemosensitivity of Pancreatic Tumor Cells
Aptamers able to bind efficiently cell-surface receptors differentially expressed in tumor and in healthy cells are emerging as powerful tools to perform targeted anticancer therapy. Here, we present a novel oligonucleotide chimera, composed by an RNA aptamer and a DNA decoy. Our assembly is able to...
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Main Authors: | David Porciani (Author), Lorena Tedeschi (Author), Laura Marchetti (Author), Lorenzo Citti (Author), Vincenzo Piazza (Author), Fabio Beltram (Author), Giovanni Signore (Author) |
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Format: | Book |
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Elsevier,
2015-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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