Rare live birth to a 48-year-old woman after embryo transfer with autologous oocyte: A case report

Objective: Advanced maternal age and decreased ovarian reserve have been challenges for assisted reproductive technology (ART). Few cases, using autologous oocytes more than 46-years-old, have previously been reported. We seek to show how the age at which autologous oocytes may successfully be emplo...

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Main Authors: Te-Wei Wu (Author), Horng-Der Tsai (Author), Hsiao-Chin Huang (Author), Hsaio-Hsuan Yang (Author), Yu-Jing Chen (Author), Hsin-Hung Wu (Author), Chen-Hsuan Wu (Author)
Format: Book
Published: Elsevier, 2022-05-01T00:00:00Z.
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Summary:Objective: Advanced maternal age and decreased ovarian reserve have been challenges for assisted reproductive technology (ART). Few cases, using autologous oocytes more than 46-years-old, have previously been reported. We seek to show how the age at which autologous oocytes may successfully be employed may be increasing. Case report: We report a 47-year-old woman with an anti-Müllerian hormone (AMH) level of 0.24 ng/mL, conceived through in vitro fertilization (IVF) using autologous oocytes. Patient was given an antagonist protocol for ovarian stimulation and one frozen-thawed embryo was transferred. The patient became pregnant. The course of her pregnancy was uneventful and she gave birth to a 3330 gm male baby by cesarean section. Conclusion: Technological advances permit women, who previously would have been considered too old to employ an autologous oocyte, to have a successful pregnancy with a live birth.
Item Description:1028-4559
10.1016/j.tjog.2022.03.028