Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects

• Main Authors: Pangilinan Faith (Author), Molloy Anne M (Author), Mills James L (Author), Troendle James F (Author), Parle-McDermott Anne (Author), Signore Caroline (Author), O'Leary Valerie B (Author), Chines Peter (Author), Seay Jessica M (Author), Geiler-Samerotte Kerry (Author), Mitchell Adam (Author), VanderMeer Julia E (Author), Krebs Kristine M (Author), Sanchez Angelica (Author), Cornman-Homonoff Joshua (Author), Stone Nicole (Author), Conley Mary (Author), Kirke Peadar N (Author), Shane Barry (Author), Scott John M (Author), Brody Lawrence C (Author)
• Format: Bog
• Udgivet: BMC, 2012-08-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Neural tube defects (NTDs) are common birth defects (~1 in 1000 pregnancies in the US and Europe) that have complex origins, including environmental and genetic factors. A low level of maternal folate is one well-established risk fac...