Considering the APOE locus in Alzheimer's disease polygenic scores in the Health and Retirement Study: a longitudinal panel study
Abstract Background Polygenic scores are a strategy to aggregate the small, additive effects of single nucleotide polymorphisms across the genome. With phenotypes like Alzheimer's disease, which have a strong and well-established genomic locus (APOE), the cumulative effect of genetic variants o...
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Main Authors: | Erin B. Ware (Author), Jessica D. Faul (Author), Colter M. Mitchell (Author), Kelly M. Bakulski (Author) |
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Format: | Book |
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BMC,
2020-11-01T00:00:00Z.
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