Glucocorticoid Is Involved in Food-Entrainable Rhythm of μ-Opioid Receptor Expression in Mouse Brainstem and Analgesic Effect of Morphine

• Autores principales: Yoshida Miyako (Autor), Kiyofuji Hiroyuki (Autor), Koyanagi Satoru (Autor), Matsuo Ayaka (Autor), Fujioka Toshihiro (Autor), To Hideto (Autor), Higuchi Shun (Autor), Ohdo Shigehiro (Autor)
• Formato: Libro
• Publicado: Elsevier, 2006-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract.: The repeated manipulation of feeding schedule has a marked influence on the chronopharmaological aspects of many drugs. In this study, we investigated the role of endogenous glucocorticoid in the mechanism by which restricting the feeding time modulates the analgesic effect of morphine. M...