Identifying and presenting key country-specific indicators related to medication adherence: a comprehensive study across European countries

• Main Authors: Tamás Ágh (Author), Kristina Garuolienė (Author), Anne Gerd Granas (Author), João Gregório (Author), Nilay Aksoy (Author), Nataliia Khanyk (Author), Maja Ortner Hadžiabdić (Author), Przemyslaw Kardas (Author), European Network to Advance Best Practices and Technology on Medication Adherence (ENABLE) (Author), Emma Aarnio (Author), Darinka Gorgieva Ackova (Author), Vesna Vujic Aleksic (Author), Martina Bago (Author), Juris Barzdins (Author), Manon Belhassen (Author), Katharina Blankart (Author), Maria A. Cordina (Author), Josip Culig (Author), Erdősi Dalma (Author), Cristina Ghiciuc (Author), Francisca Leiva Fernández (Author), Pilar Barnestein Fonseca (Author), Freyja Jonsdottir (Author), Fatjona Kamberi (Author), Barbora Kostalova (Author), Urška Nabergoj Makovec (Author), Valentina Marinković (Author), Enrica Menditto (Author), Vildan Mevsim (Author), Zornista Mitkova (Author), Herbolka Natalka (Author), Christos Petrou (Author), Panagiotis Petrou (Author), Guenka Petrova (Author), Mitar Popovic (Author), Katarina Smilkov (Author), Ioanna Tsiligianni (Author), Marie Paule Schneider Voirol (Author), Daisy Volmer (Author), Martin Wawruch (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1663-9812; 10.3389/fphar.2024.1390629
• Keywords: medication adherence; persistence; health policy; indicator; Europe; Therapeutics. Pharmacology; RM1-950
• Source: Frontiers in Pharmacology, Vol 15 (2024)

This study tackles the critical challenge of medication non-adherence in healthcare by pinpointing indicators related to medication adherence (IRMAs) across 39 European countries and Israel. Utilizing a structured expert survey methodology within the European Network to Advance Best Practices and Technology on Medication Adherence (ENABLE; COST Action CA19132), our research identified key country-specific IRMAs and collected data on these indicators to understand the multifaceted nature of medication adherence. The research was conducted in two phases: firstly, defining key IRMAs through a two-round expert survey, and secondly, gathering country-specific data on these IRMAs through literature reviews and additional expert surveys. The study revealed a diverse range of 26 top-ranked IRMAs, including six related to country characteristics, four to social/economic factors, three each to therapy-related and patient-related factors, one to condition-related factors, and nine to healthcare system-related factors. The availability of country-specific data on these IRMAs varied among the countries, highlighting the need for more comprehensive data collection and research. The findings from this study not only underscore the complexity of predicting medication adherence but also lay the groundwork for developing targeted, country-specific interventions to improve adherence. Moreover, this research offers valuable insights for policymakers, highlighting the importance of understanding the multifaceted nature of medication adherence and offering a valuable resource in formulating targeted health policies to enhance health outcomes and reduce the economic burden associated with medication non-adherence.