Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Asıl Yazarlar: Maral Mokhtari (Yazar), Farzaneh Mostanbet (Yazar), Saideh Nekooee Fard (Yazar), Golsa Shekarkhar (Yazar), Mozhdeh Sepaskhah (Yazar), Maryam Sadat Sadati (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...