Drug-drug interaction prediction of ziritaxestat using a physiologically based enzyme and transporter pharmacokinetic network interaction model
Abstract Ziritaxestat, an autotaxin inhibitor, was under development for the treatment of idiopathic pulmonary fibrosis. It is a substrate of cytochrome P450 3A4 (CYP3A4) and P‐glycoprotein and a weak inhibitor of the CYP3A4 and OATP1B1 pathways. We developed a physiologically based pharmacokinetic...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2023-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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