Beyond Adherence Thresholds: A Simulation Study of the Optimal Classification of Longitudinal Adherence Trajectories From Medication Refill Histories

• المؤلفون الرئيسيون: Samuel S. Allemann (مؤلف), Dan Dediu (مؤلف), Alexandra Lelia Dima (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background: The description of adherence based on medication refill histories relies on the estimation of continuous medication availability (CMA) during an observation period. Thresholds to distinguish adherence from non-adherence typically refer to an aggregated value across the entire observation...